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23 Best Acne Spot Treatments of 2020 and Beyond

23 Best Acne Spot Treatments of 2020 and Beyond

Acnes are one of the worst things that can happen to you during the teenage years. In this article, we'll review 23 of the best acne spot treatments you can use in 2020 and beyond.

We are very self-aware during these years, and the last thing we need is something affecting our confidence. It also affects how we behave with potential love interests. The only good thing about acne is that you can treat it! 

Nowadays, there are lots of different medications that you can use for this problem. Some of them are super effective. 

Here is our list of the best acne spot treatments that you can buy.


1. Clean & Clear Advantage Spot Treatment

This transparent gel is simply perfect! A lot of dermatologists suggest it for a good reason. It has 2% salicylic acid, which does a great job of affecting acne. As soon as you feel acne, you should apply it to your skin. It works quickly, and the next morning, you probably won't have acne on your skin!

2. Neutrogena Light Therapy Acne Spot Treatment

Neutrogena is a world-renowned company that has a solution to various medical problems. One of them is, of course, acne. It is very close to perfect medicine. As the name implies, this product is made to resemble light therapy. It works by killing bacteria that are causing the issue. Neutrogena's impact on acne is superb.

3. Dermatologica Breakout Control

Dermatologica was meant to provide support to the most extreme cases. It offers complete control of an area affected by acne, but you can also use it for one specific spot. The product relies on a probiotic called lactobacillus ferment that is able to remove everything from the pores while adding zinc sulfate for inflammation. One interesting component is colloidal silver that also works as an antibacterial substance. You can use it at any time during the day. 

4. Peter Thomas Roth Acne Spot and Area Treatment

Like some other creams on this list with best acne spot treatments, Peter Thomas Roth relies on colloidal sulfur to treat problematic spots. It has around 5% of this substance, which is more than enough to destroy bacteria and stifle their growth. This will leave your spores empty and unclogged, effectively treating the issue. Peter Thomas Roth cream is applied before sleep and will resolve the issue by the morning.

5. Origins Super Spot Remover

This product is transparent, thus barely visible. No matter when you apply it, people will not notice it's there. When applied on your skin, it will leave a small tingling feeling. Origins Super Spot Remover uses a mixture of salicylic acid and oregano oil, both of which are super effective. It also has apple and cucumber extracts, which add to its effectiveness but also provide a better smell to the cream. All those vitamins and minerals will nurture your skin, preventing future issues and making your face that much more appealing.

6. Murad Blemish Control Rapid Relief Spot Treatment

Sulfur and salicylic acid are probably the most common ingredients for all skin creams. Murad Blemish Control took this to heart and made a formula that focuses on these two super-effective substances. However, that doesn’t mean that it doesn’t work. In fact, this product is one of the best items you can buy for this particular medical condition. 

7. Boscia Charcoal Imperfection Corrector

Like any other type of corrector, this product is meant to treat any imperfection on your face. It works by combining salicylic acid, charcoal, as well as calamine. The formula is completely natural, safe, and it has a long-lasting impact on skin health. It can be used at any time of the day, and it is completely unnoticeable, making it a perfect solution for acne.This corrector is one of the best acne spot treatments one can try in 2020.

8. Mario Badescu Drying Lotion

Bacteria that are causing acne can be really resilient. However, that doesn't mean it cannot be beaten. With enough salicylic acid, it will be taken care of in an instant. Mario Badescu’s Lotion focuses on this substance and also ads sulfur for disinfection as well as calamine that reduces redness. While it can be used at any time, the lotion is best suited for nightly use.

9. Philosophy Clear Days head

Like most other items on the list, this is an invisible gel that cannot be distinguished from a regular cream. It can be applied at any time with no consequences. The mixture of salicylic acid and glycolic acid helps to deal with bacteria. There are also some other substances such as dimethicone and squalene that make for a perfect medicine. It will work on your skin within a day. Just put it in the evening, and there will be no more issues in the morning. 

10. Osmia Organics Spot Treatment

Osmia relies on a rollerball to administer the medicine. It uses various essential oils, such as lemon, lavender, thyme, etc. This makes for an unbelievably lovely smelling ointment. Osmia deals with acne, as well as all other symptoms such as redness and inflammation. 

11. La Roche-Posay Effaclar Duo

When mentioning skin creams, it is hard to neglect La Roche-Posay. Effaclar, in particular, is a very popular solution, which is why people all over the world use it for battling this issue. It comes in the form of a gel that has benzoyl peroxide. This substance is able to penetrate spores much better than some other products. It also has lipohydroxy acid, which exfoliates, thus reducing inflammation. 

12. Skyn Iceland Blemish Dots with Salicylic Acid

Of course, there are also effective skin treatments that don't come in the form of a cream or gel. For example, Skyn Iceland is in the form of a sticker. According to the manufacturer, one pack can remove up to 48 acnes. It is straightforward to use, doesn't leave any trace, and doesn't have the same properties as creams. You just have to put one of these sticks on and leave it be overnight.

13. Kiehl’s Breakout Control Targeted Acne Spot Treatment

If you're looking for an extremely quick, yet powerful solution, you can't go wrong with this one. The product removes acne in an instant, and it is recommended that you use it overnight. The only issue is its strong smell. However, this is a small price to pay for such an effective acne spot treatment.

14. Neutrogena On the Spot Acne Treatment

As you can presume, some of these companies have several good products that can be used for acne. This is the case with Neutrogena. Besides their Light Therapy acne medicine, they also have On the Spot Acne Treatment. The most important thing about this item is the fact it will kill bacteria without clogging your skin. As such, it is especially great for skin that is prone to these issues. Another good side of On the Spot is that it doesn’t dry out your skin.

15. Paula’s Choice Clear Daily Skin Clearing Treatment 

Paula’s Choice relies on benzoyl peroxide for topical acne spot treatment. It has 2.5% of this substance, which is great for acne that is on your face but also prevents future occurrences. Most women use it as a daily treatment because you can put makeup over it. While the medicine is used to cover specific spots, you can also cover your whole face with it. Make sure to be careful with it, though, as benzoyl peroxide can work almost as a bleach.

16. Peace Out Acne Healing Dots 

Although acne is an issue common for teenagers, most of the products look bland. Peace Out is an item geared towards this age group, which you can see based on its packaging. However, Peace Out is not a gimmick; it is a really good acne spot treatment! It works by eliminating bacteria and fixing the infection. The product is based on hydrocolloid technology, which is relatively rare for acne medication. Nevertheless, it produces amazing and quick results. Among others, it also has aloe, which helps soothe the skin.

17. ProactivMD Adapalene Gel

ProactivMD is a gel that is barely noticeable. You can put it at any time of the day without worrying. According to experts, it shows lots of potentials when dealing with comedonal acne, or in other words, blackheads, and whiteheads. It also has some additional perks treating redness and inflammation. While not as common as some other items on our list, there are a lot of customers who swear in this product. Some of them go as far as to claim that this is the only item that helps them out!

18. Acne Pimple Master Patch

Patches are not that common among acne products, but you can find them here and there. Cosrx’s medicine is waterproof and ideal during the summer. You can do a lot of different activities while wearing it. However, most people tend to use it overnight. In the end, not everyone is prepared to walk around with a patch on their face. One of the biggest advantages is that it helps reduce acne scarring. 

19. EradiKate Acne Treatment 

Named after Kate Somersville, this item is one of the best acne spot treatments you can buy on the open market. It is especially good for all the pimples that you feel under your skin, but can’t get to. The product relies on ingredients such as zinc, sulfur, exfoliating BHA’s, which is more than enough to deal with various acne-related issues. 

20. Salicylic Acid 2% Solution by The Ordinary 

Oftentimes, companies do their best to create intricate products that would help us treat some basic conditions. The same goes for acne. While some of them can be really persistent and troublesome, most can be treated easily. This is why simple salicylic acid can do wonders for your skin. The Ordinary has created a product that is very simplistic in nature. Even its packaging looks dull. However, it will work wonders for your skin. Keep in mind that this solution is really strong, so some precautionary measures are needed if you have sensitive skin.

21. Dynaspot Eve Lom

Dynatspot Eve Lom impacts your skin in numerous ways. Besides the fact it eliminates bacteria that is causing the issue, it also helps protect your skin. Best yet, it makes it much softer, and it reduces redness that commonly appears. The product comes in the form of a gel and can be used at any time of a day. 

22. Peach Slices Acne Spot Dots 

Peach Slices Acne Spot Dots are translucent patches that can be used at any time of a day. They have a clear advantage over some other acne spot treatments as you can put them during a day without having to worry about your physical appearance. Each patch has the necessary ingredients that are able to “put” out the impurities and eliminate bacteria. 

23. SpotLite Acne Treatment Device 

As we’ve mentioned, the products on this list are either creams, patches, or gels. This is what makes SpotLite such a unique acne spot treatment. It isn’t a medicine, but instead a small device that is meant to treat your skin. It has a red light that eliminates inflammation and the blue one that deals with bacteria. Furthermore, while it can be used for regular pimples, it is mainly geared towards acne and extremely sensitive skin. You can notice the first results after a few weeks.


The market for acne treatment drugs has never been better. Something that was previously perceived as an enormous issue for both teenagers and adults is now just an afterthought.

Keep in mind that while some of these products have similar ingredients, that may work differently on your skin. Furthermore, some of them may cause issues to sensitive skin. So, it is always better to consult a doctor before proceeding with any of the 23 acne spot treatments mentioned in this article.

You can also try several creams or gels, and see which one fits your skin the best!

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